Health Policy, Economics and Sociology

The Impact of Untreated Sexually Transmitted Diseases in Women

Aksa Thomas — Sat, 15 Feb 2025 00:00:00 +0400

Introduction: Women who have untreated sexually transmitted infections face serious physical, psychological, and social repercussions, making them a serious public health concern. to examine the long-term physical, social, and economic effects of untreated STDs in women with an emphasis on their effects on reproductive health and general well-being. Methodology: A comprehensive literature review was conducted, analysing peer-reviewed studies on the effects of untreated sexually transmitted diseases in women. Results: Untreated sexually transmitted diseases cause substantial psychological discomfort in addition to serious reproductive health issues like infertility and pelvic inflammatory disease. Social stigma and cultural hurdles restrict women from obtaining timely care, especially in impoverished populations. Additionally, women's mental and physical health is affected by the convergence of sexually transmitted diseases with intimate partner violence and sexual trauma. Conclusion: A comprehensive strategy should include regular screening, more sex education, improved access to healthcare, less stigma, and integrated mental health aid to enhance the health and quality of life of impacted women.

Impact of gut microbiome dysbiosis on prostate cancer

Antony Thomas — Thu, 20 Feb 2025 00:00:00 +0400

Introduction: The gut microbiome is integral for regulating metabolism, immune functions, and inflammation, with growing evidence suggesting its involvement in the growth and course of prostate cancer (PCa). This review examines the effect of gut microbiome alterations in influencing PCa incidence and risk, factors leading to prostate cancer development, advancement, and resistance to treatment. Methodology: A comprehensive literature review was conducted, analysing peer-reviewed studies on the effects of gut microbiome dysbiosis on prostate cancer. Results: Distinct microbial patterns such as a rise in pro-inflammatory Bacteroides massiliensis and a decrease in anti-inflammatory Faecalibacterium prausnitzii seen in PCa patients which can be used as a biomarker for making a diagnosis of prostate cancer from other prostate-related conditions. Also, the production of bile acids and short-chain fatty acids by gut bacteria can interfere with hormone synthesis, and a diet high in fat and reduced fiber can lead to dysbiosis eventually causing PCa. Conclusion: The study underscores the relevance of gut microbiome dysbiosis and its relation to androgen regulation, inflammatory reactions, and metabolic pathways—all of which have a role in the development of prostate cancer. A good dietary approach and probiotics together with traditional methods like androgen restriction therapy can lead to well-balanced outcomes in patients.

Understanding the Gut-Brain Connection: Exploring Its Impact on Neurological Health, Neurodegenerative Diseases, and Depression

Akhil Krishnan Vikraman Pillai — Thu, 20 Feb 2025 00:00:00 +0400

Introduction: The microbiota gut-brain axis or the (MGBA) that incorporates gut microbiota (GM) is known to control the defensive system of our body along with the well-being of the central nervous system (CNS). The GM represents parasitic microorganisms that if in abnormal ratios throughout the body, may result in exposure to diseases, for example, Alzheimer’s and Parkinson’s. This research aims to clarify the molecular pathways through which GM dysbiosis impacts neurological health and will explore the effectiveness of probiotics and Synbiotics in restoring GM balance to improve brain function. Methodology: A comprehensive literature review was conducted, analysing peer-reviewed studies on the microbiome studies, the implications of probiotics, Synbiotics, and changes in nutrition on the composition of GM and the neuroinflammatory response of an organism. Results: The data indicate that these approaches assist in the re-establishment of adequate diversity in the GM population which helps to reduce the extent of neuroinflammation, stabilize the functioning of neurotransmitter deregulation, and enhance cognitive performance. The findings indicate the critical potential of biological agents targeting gut microbiota in the treatment of some neurological conditions. Conclusion: the modulating of GM represents a new understanding and mechanisms that can help deal with issues associated with brain health and manage prevalent complications of neurodegenerative diseases while reiterating the need for microbiome balance for the optimal functioning of CNS.